Objectives:
@EN Endoscopic variceal ligation is well established method of treatment for esophageal varices whereas for gastric varices there has not been any systematic report of its use as a method of treatment. To evaluated its possible clinical
application, the
band ligation(banding) and the method of band ligation in conjuction with submucosal ethanolamine injection(banding with sclero) were tested on canine stomach, and results were assessed.
@ES Methods:
@EN The experimental subjects were 10 mongrel dogs, which were divided into 2 groups(Banding group, 5 subjects; Banding with sclero group: banding with submucosal injection of 0.5cc of 5% ethanolamine oleate on each of 2~3 places around ligation
site, 5
subjects). Each group was performed examination at 1, 7, 14, 17, 18, 19, 20, and 21 days. The dogs were sacrificed at 21days. Autopsy was performed; morphological and histological observations were made.
@ES Results: In banding group observations were made as follows:
@EN 9 sites(6.8%)-significant bleeding, 6 sites(4.5%)-perforation. 18 sites(13.6%)-muscle layer injury. The average size of post-operative-ulcers was 16.7mm(8.5-23.0mm). The rate of hemorrage was significant greater for banding than for banding
with
sclero. It is possible that the practice of submucosal injections of ethanolamine oleate around ligation sites produce ischemia and inflammatory response in the submucosa, which may help to reduce the chance of bleeding from ligation-induced
ulcers.
@ES Conclusion:
@EN The band ligation on gastric wall accompanies risks of deep ulceration and hemorrhage. Hemorrhage may be prevented via banding with sclero.(Ko-rean J Gastrointest Endosc 16:145~155, 1996)
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